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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107159Generated: October 25, 2026

Ammonia → 5-{1-Ethoxycarbonyl-1-[2-(3-phenylureido)thiazol-4-yl]methylene}rhodanine acetic acid

https://huagongshe.com/reaction/2107159

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantAmmonium ChlorideHCID 25517—
ReactantRhodanineHCID 1201546—
ReactantEthyl 2-(3-phenylureido)thiazol-4-ylglyoxylateHCID 15053489—
SolventEthanolHCID 702—
Product5-{1-Ethoxycarbonyl-1-[2-(3-phenylureido)thiazol-4-yl]methylene}rhodanine acetic acidHCID 54136396—

Reaction Steps

Following a procedure similar to that described in Example 1, the desired compound was prepared from 3 g of ethyl 2-(3-phenylureido)thiazol-4-ylglyoxylate, 1.25 g of rhodanine, 1 g of ammonium chloride 1 ml of 28% v/v aqueous ammonia and 10 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04933355
Source datasetuspto-grants-1990_06
ORD IDord-21a70c9232dd45a8ba84d52482b134e2
Source noteuspto-grants-1990_06