HRID2107166

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8082

Piperidine

C5H11N

HCID2770836

(2,4-dioxo-1,3-thiazolidin-3-yl)acetic acid

C5H5NO4S

结构：O=Cc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1

HCID15053569

未命名化合物

PRODUCTS

生成物

结构：C1CC[NH2+]CC1.O=C([O-])CN1C(=O)SC(=Cc2csc(NC(c3ccccc3)(c3ccccc3)c3ccccc3)n2)C1=O

HCID73454615

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Following a procedure similar to that described in Example 17, the desired compound was prepared from 2.3 g of 2-tritylaminothiazole-4-carbaldehyde, 0.9 g of 2,4-dioxothiazolidine-3-acetic acid, 0.9 g of piperidine and 20 ml of ethanol. The resulting product was a pale yellow powder having the following physical properties.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-721fbfc7608c4142b3334da359872d35
来源数据集: uspto-grants-1990_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04933355
来源说明: uspto-grants-1990_06

反应 SMILES

[C:1]([NH:20][C:21]1[S:22][CH:23]=[C:24]([CH:26]=O)[N:25]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:28]=[C:29]1[N:33]([CH2:34][C:35]([OH:37])=[O:36])[C:32](=[O:38])[CH2:31][S:30]1.[NH:39]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1>C(O)C>[O:28]=[C:29]1[N:33]([CH2:34][C:35]([O-:37])=[O:36])[C:32](=[O:38])[C:31](=[CH:26][C:24]2[N:25]=[C:21]([NH:20][C:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)([C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[S:22][CH:23]=2)[S:30]1.[NH2+:39]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1