反应详情

A mixture comprising 1 g of 2-(3-phenylureido)thiazole-4-carbaldehyde, 0.85 g of rhodanine-3-acetic acid, 0.76 g of piperidine and 15 ml of ethanol was stirred at room temperature for 2 hours, and the resulting mixture was left to stand overnight. The crystals which precipitated out were collected by filtration dispersed in dilute aqueous hydrochloric acid, and washed with stirring for 30 minutes. The resulting crystalline product was recrystallized from a mixture of acetic acid and ethyl acetate, giving 0.78 g of the desired compound as an orange powder.

1. waitthe resulting mixture was left
2. waitto stand overnight
3. customThe crystals which precipitated out
4. filtrationwere collected by filtration
5. additiondispersed in dilute aqueous hydrochloric acid
6. washwashed
7. stirringwith stirring for 30 minutes
8. customThe resulting crystalline product was recrystallized from a mixture of acetic acid and ethyl acetate