Piperidine → 5-[2-(3-Phenylureido)thiazol-4-ylmethylene]rhodanine

HRID 2107172Notes

Reaction equation

HRID 2107172 reaction equation
[C:1]1([NH:7][C:8](=[O:17])[NH:9][C:10]2[S:11][CH:12]=[C:13]([CH:15]=O)[N:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[S:18]1[CH2:24][C:22](=[O:23])[NH:21][C:19]1=[S:20].N1CCCCC1>C(O)C>[C:1]1([NH:7][C:8](=[O:17])[NH:9][C:10]2[S:11][CH:12]=[C:13]([CH:15]=[C:24]3[S:18][C:19](=[S:20])[NH:21][C:22]3=[O:23])[N:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 8082PiperidineHCID 1201546RhodanineHCID 150535142-(3-Phenylureido)thiazole-4-carbaldehyde

Product 1

HCID 540735455-[2-(3-Phenylureido)thiazol-4-ylmethylene]rhodanine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 24, the desired compound was prepared from 1 g of 2-(3-phenylureido)thiazole-4-carbaldehyde, 0.6 g of rhodanine, 0.75 g of piperidine and 15 ml of ethanol. The resulting product was a yellow-brown powder having the following physical properties.

Sources & evidence

ORD record
ord-11b893962a8643bda9f2a157ffe70b34
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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