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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107193Generated: October 31, 2026

Ammonia → 5-[2-(3-Phenylureido)thiazol-4-ylmethylene]thiazolidine-2,4-dione

https://huagongshe.com/reaction/2107193

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantThiazolidinedioneHCID 5437—
ReactantAmmonium ChlorideHCID 25517—
Reactant2-(3-Phenylureido)thiazole-4-carbaldehydeHCID 15053514—
SolventEthanolHCID 702—
Product5-[2-(3-Phenylureido)thiazol-4-ylmethylene]thiazolidine-2,4-dioneHCID 53682958—

Reaction Steps

Following a procedure similar to that described in Example 1, the desired compound was prepared from 1.1 g of 2-(3-phenylureido)thiazole-4-carbaldehyde, 0.52 g of 2,4-thiazolidinedione, 0.6 g of ammonium chloride, 0.6 ml of 28% v/v aqueous ammonia and 20 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04933355
Source datasetuspto-grants-1990_06
ORD IDord-4590afc7eebd4b96b64f66fe402339d6
Source noteuspto-grants-1990_06