Ammonia → HCID 54571816, Verbindung

HRID 2107198Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2107198
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[S:23])[NH:10][C:11]2[S:12][CH:13]=[C:14]([C:16](=O)[C:17]([O:19][CH2:20][CH3:21])=[O:18])[N:15]=2)=[CH:4][CH:3]=1.[S:24]1[CH2:30][C:28](=[O:29])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:25]1=[S:26].[Cl-].[NH4+].N>C(O)C>[CH2:20]([O:19][C:17]([C:16](=[C:30]1[S:24][C:25](=[S:26])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:28]1=[O:29])[C:14]1[N:15]=[C:11]([NH:10][C:9]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)=[S:23])[S:12][CH:13]=1)=[O:18])[CH3:21]

Komponenten

6

Edukt 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053510Ethyl 2-(3-p-fluorophenylthioureido)thiazol-4-ylglyoxylate

Produkt 1

HCID 54571816HCID 54571816, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Following a procedure similar to that described in Example 1, the desired compound was prepared from 550 mg of ethyl 2-(3-p-fluorophenylthioureido)thiazol-4-ylglyoxylate, 29 mg of rhodanine-3-acetic acid, 150 mg of ammonium chloride, 0.15 ml of 28% v/v aqueous ammonia and 10 ml of ethanol. The resulting product was in the form of yellow acicular crystals having the following physical properties.

Quellen und Nachweise

ORD-Eintrag
ord-f3235a84162d4031bb776146a4e10ce3
Quelldatensatz
uspto-grants-1990_06
Patentnummer
US04933355

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