Hydrochloric Acid → Ethyl 5-(2-anilinothiazol-4-ylmethylene)rhodanine-3-acetate

HRID 2107200Notes

Reaction equation

HRID 2107200 reaction equation
[NH:1]([C:8]1[S:9][CH:10]=[C:11]([CH:13]=[C:14]2[S:18][C:17](=[S:19])[N:16]([CH2:20][C:21]([OH:23])=[O:22])[C:15]2=[O:24])[N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:25](O)[CH3:26].Cl>O1CCOCC1>[NH:1]([C:8]1[S:9][CH:10]=[C:11]([CH:13]=[C:14]2[S:18][C:17](=[S:19])[N:16]([CH2:20][C:21]([O:23][CH2:25][CH3:26])=[O:22])[C:15]2=[O:24])[N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 539160375-(2-Anilinothiazol-4-ylmethylene)rhodanine-3-acetic acid

Product 1

HCID 53848336Ethyl 5-(2-anilinothiazol-4-ylmethylene)rhodanine-3-acetate

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Following a procedure similar to that described in Example 30, the desired compound was prepared from 1 g of 5-(2-anilinothiazol-4-ylmethylene)rhodanine-3-acetic acid, 2 g of ethanol and 10 ml of a 4N dioxane solution of hydrogen chloride. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-dbd2a1c3d9fb4ae98d956527424374d9
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…