Hydrochloric Acid → Ethyl 5-(2-diphenylmethylaminothiazol-4-ylmethylene)-rhodanine-3-acetate

HRID 2107205Notes

Reaction equation

HRID 2107205 reaction equation
[C:1]1([CH:7]([NH:14][C:15]2[S:16][CH:17]=[C:18]([CH:20]=[C:21]3[S:25][C:24](=[S:26])[N:23]([CH2:27][C:28]([OH:30])=[O:29])[C:22]3=[O:31])[N:19]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:32](O)[CH3:33].Cl>O1CCOCC1>[C:1]1([CH:7]([NH:14][C:15]2[S:16][CH:17]=[C:18]([CH:20]=[C:21]3[S:25][C:24](=[S:26])[N:23]([CH2:27][C:28]([O:30][CH2:32][CH3:33])=[O:29])[C:22]3=[O:31])[N:19]=2)[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 545717655-(2-Diphenylmethylaminothiazol-4-ylmethylene)rhodanine--acetic acid

Product 1

HCID 53848027Ethyl 5-(2-diphenylmethylaminothiazol-4-ylmethylene)-rhodanine-3-acetate

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Following a procedure similar to that described in Example 30, the desired compound was prepared from 0.6 g of 5-(2-diphenylmethylaminothiazol-4-ylmethylene)rhodanine--acetic acid, 7.7 g of ethanol and 15 ml of a 4N dioxane solution of hydrogen chloride. The resulting product was a greenish-yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-200f1f9e8cac49cbae8d4844658e95fd
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…