Benzene, 1-isocyanato-2-methoxy- → HCID 15053490, compound

HRID 2107223Notes

Reaction equation

HRID 2107223 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH3:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N:22]=[C:23]=[O:24]>CN(C)C=O>[CH3:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[NH:22][C:23](=[O:24])[NH:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1

Participants

4

Reactant 2

HCID 69695Benzene, 1-isocyanato-2-methoxy-HCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 15053490HCID 15053490, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that described in preparation 1, the desired compound was prepared from 5 g of ethyl 2-aminothiazol-4-ylglyoxylate, 4.5 g of o-methoxyphenyl isocyanate and 40 ml of dimethylformamide. The resulting product was a yellow powder having the following physical properties.

Workup

  1. customthat described in preparation 1

Sources & evidence

ORD record
ord-c80a2a7f9ec84a3c906faa05d062892d
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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