3,4-Dichlorophenyl isocyanate → HCID 15053496, compound

HRID 2107228Notes

Reaction equation

HRID 2107228 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[Cl:14][C:15]1[CH:16]=[C:17]([N:22]=[C:23]=[O:24])[CH:18]=[CH:19][C:20]=1[Cl:21]>CN(C)C=O>[Cl:14][C:15]1[CH:16]=[C:17]([NH:22][C:23](=[O:24])[NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=2)[CH:18]=[CH:19][C:20]=1[Cl:21]

Participants

4

Reactant 2

HCID 76073,4-Dichlorophenyl isocyanateHCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 15053496HCID 15053496, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that described in Preparation 1, the desired compound was prepared from 10 g of ethyl 2-aminothiazol-4-ylglyoxylate, 10 g of 3,4-dichlorophenyl isocyanate and 100 ml of dimethylformamide. The resulting product was a pale yellow powder having the following physical properties.

Workup

  1. customthat described in Preparation 1

Sources & evidence

ORD record
ord-a5dbe4eb30f34962a09108539625870b
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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