Phenyl isocyanate → HCID 15053516, compound

HRID 2107239Notes

Reaction equation

HRID 2107239 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:15])[C:8]([O:10][CH2:11][CH:12]([CH3:14])[CH3:13])=[O:9])[N:6]=1.[C:16]1([N:22]=[C:23]=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>O1CCCC1>[C:16]1([NH:22][C:23](=[O:24])[NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7](=[O:15])[C:8]([O:10][CH2:11][CH:12]([CH3:13])[CH3:14])=[O:9])[N:6]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 15053527HCID 15053527, compound

Product 1

HCID 15053516HCID 15053516, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following a procedure similar to that described in Preparation 1, the desired compound was prepared from 1 g of isobutyl 2-aminothiazol-4-ylglyoxylate, 620 mg of phenyl isocyanate and 10 ml of tetrahydrofuran. The resulting product was a pale yellow powder having the following physical properties.

Workup

  1. customthat described in Preparation 1

Sources & evidence

ORD record
ord-14e9cc911f0142aa8ead24f70781a8c2
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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