5-Isocyanato-1,2,3-trimethoxybenzene → HCID 15053517, compound

HRID 2107245Notes

Reaction equation

HRID 2107245 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([N:26]=[C:27]=[O:28])[CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23]>CN(C)C=O>[CH3:14][O:15][C:16]1[CH:17]=[C:18]([NH:26][C:27](=[O:28])[NH:1][C:2]2[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=2)[CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23]

Participants

4

Reactant 2

HCID 5177665-Isocyanato-1,2,3-trimethoxybenzeneHCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 15053517HCID 15053517, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that described in Preparation 1, the desired compound was prepared from 4.3 g of ethyl 2-aminothiazol-4-ylglyoxylate, 5 g of 3,4,5-trimethoxyphenyl isocyanate and 30 ml of dimethylformamide. The resulting product was a yellow powder having the following physical properties.

Workup

  1. customthat described in Preparation 1

Sources & evidence

ORD record
ord-addf775677044594b33517cd719ea0bc
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…