Benzyl isocyanate → HCID 15053519, compound

HRID 2107252Notes

Reaction equation

HRID 2107252 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[CH2:14]([N:21]=[C:22]=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>CN(C)C=O>[CH2:14]([NH:21][C:22](=[O:23])[NH:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[O:13])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 76639Benzyl isocyanateHCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 15053519HCID 15053519, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following a procedure similar to that described in Preparation 1, the desired compound was prepared from 4.7 g of ethyl 2-aminothiazol-4-ylglyoxylate, 4.5 g of benzyl isocyanate and 30 ml of dimethylformamide. The resulting product was a yellow powder having the following physical properties.

Workup

  1. customthat described in Preparation 1

Sources & evidence

ORD record
ord-b7b9569d11924abfb8eb01d075e9910b
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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