HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenyl isothiocyanate → Ethyl 2-(3-p-fluorophenylthioureido)thiazol-4-ylglyoxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenyl isothiocyanate | HCID 15241 | — |
| Reactant | Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate | HCID 4356513 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Ethyl 2-(3-p-fluorophenylthioureido)thiazol-4-ylglyoxylate | HCID 15053510 | — |
Reaction Steps
Following a procedure similar to that described in Preparation 1, the desired compound was prepared from 5 g of ethyl 2-aminothiazol-4-ylglyoxylate, 4.6 g of p-fluorophenyl isothiocyanate and 20 ml of dimethyl sulfoxide. The resulting product was a pale yellow powder having the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-09f912b3b7b148839ce974fd38c85d0f |
| Source note | uspto-grants-1990_06 |