Ethyl bromopyruvate → HCID 15053539, compound

HRID 2107273Notes

Reaction equation

HRID 2107273 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH2:11])=[S:10])=[CH:4][CH:3]=1.Br[CH2:13][C:14](=O)[C:15]([O:17][CH2:18][CH3:19])=[O:16]>C(O)C>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]2[S:10][CH:13]=[C:14]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[N:11]=2)=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 66144Ethyl bromopyruvateHCID 6930614-Fluorophenylthiourea

Product 1

HCID 15053539HCID 15053539, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Preparation 42 was repeated, but using 12 g of p-fluorophenylthiourea, 14.8 g of ethyl bromopyruvate, and 120 ml of ethanol, giving the title compound as pale yellow prisms.

Workup

  1. customThe reaction described in Preparation 42

Sources & evidence

ORD record
ord-76548fe2596748cfb6c7f44ba938a191
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…