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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107273Generated: October 25, 2026

Ethyl bromopyruvate → Ethyl 4-((4-fluorophenyl)amino)-3,5-thiazolecarboxylate

https://huagongshe.com/reaction/2107273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromopyruvateHCID 66144—
Reactant4-FluorophenylthioureaHCID 693061—
SolventEthanolHCID 702—
ProductEthyl 4-((4-fluorophenyl)amino)-3,5-thiazolecarboxylateHCID 15053539—

Reaction Steps

The reaction described in Preparation 42 was repeated, but using 12 g of p-fluorophenylthiourea, 14.8 g of ethyl bromopyruvate, and 120 ml of ethanol, giving the title compound as pale yellow prisms.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04933355
Source datasetuspto-grants-1990_06
ORD IDord-76548fe2596748cfb6c7f44ba938a191
Source noteuspto-grants-1990_06