Triethylamine → HCID 15053573, compound

HRID 2107277Notes

Reaction equation

HRID 2107277 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[S:11][CH:12]=[C:13]([CH2:15][OH:16])[N:14]=2)=[CH:5][CH:4]=1.C(N(CC)CC)C>CS(C)=O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([NH:9][C:10]2[S:11][CH:12]=[C:13]([CH:15]=[O:16])[N:14]=2)=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 15053556HCID 15053556, compound

Product 1

HCID 15053573HCID 15053573, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The reaction described in Preparation 44 was repeated, but using 3 g of 2-p-anisidinothiazol-4-yl-methanol, 6.1 g of pyridine sulfur trioxide complex, 5.3 ml of triethylamine and 90 ml of dimethyl sulfoxide, giving the title compound as pale brown crystals.

Workup

  1. customThe reaction described in Preparation 44

Sources & evidence

ORD record
ord-939d4a7f8449472989fe5383d809c8d6
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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