HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-Ethylaminothiazol-4-ylmethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-Thiazolecarboxylic acid, 2-(ethylamino)-, ethyl ester | HCID 15053541 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Ethylaminothiazol-4-ylmethanol | HCID 15053558 | — |
Reaction Steps
The reaction described in Preparation 17 was repeated but using 10 g of ethyl 2-ethylaminothiazole-4-carboxylate, 3.8 g of sodium borohydride, 70 ml of methanol and 150 ml of tetrahydrofuran, giving the title compound as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-18504b965a984856b05198669e03bf46 |
| Source note | uspto-grants-1990_06 |