HCID 15053543, compound → HCID 15053561, compound

HRID 2107288Notes

Reaction equation

HRID 2107288 reaction equation
[C:1]1([N:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:8]2[S:9][CH:10]=[C:11]([C:13](OCC)=[O:14])[N:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[C:18]1([N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]2[S:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

4

Reactant 2

HCID 15053543HCID 15053543, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 15053561HCID 15053561, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction described in Preparation 15 was repeated, but using 27 g of ethyl 2-diphenylaminothiazole-4-carboxylate, 4.7 g of lithium aluminum hydride and 400 ml of tetrahydrofuran, giving the title compound as pale yellow prisms.

Workup

  1. customThe reaction described in Preparation 15

Sources & evidence

ORD record
ord-ff9b342d691c47c2a3af3c66986997d2
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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