Triethylamine → HCID 15053580, compound

HRID 2107293Notes

Reaction equation

HRID 2107293 reaction equation
[N:1]1([C:7]2[S:8][CH:9]=[C:10]([CH2:12][OH:13])[N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(N(CC)CC)C>CS(C)=O>[N:1]1([C:7]2[S:8][CH:9]=[C:10]([CH:12]=[O:13])[N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 15053562HCID 15053562, compound

Product 1

HCID 15053580HCID 15053580, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The reaction described in Preparation 44 was repeated, but using 2.4 g of 2-piperidinothiazol-4-ylmethanol, 5.8 g of sulfur trioxide pyridine complex, 3.7 g of triethylamine and 30 ml of dimethyl sulfoxide, giving the title compound as pale orange prisms.

Workup

  1. customThe reaction described in Preparation 44

Sources & evidence

ORD record
ord-444c330f0269424a815eee80f2d040cf
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…