HCID 15053546, compound → HCID 15053563, compound

HRID 2107295Notes

Reaction equation

HRID 2107295 reaction equation
[N:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12](OCC)=[O:13])[N:11]=2)[CH2:6][CH2:5][S:4][CH2:3][CH2:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[N:1]1([C:7]2[S:8][CH:9]=[C:10]([CH2:12][OH:13])[N:11]=2)[CH2:6][CH2:5][S:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 15053546HCID 15053546, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 15053563HCID 15053563, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction described in Preparation 15 was repeated, but using 1.5 g of ethyl 2-(thiomorpholin-4-yl)thiazole -4-carboxylate, 0.26 g of lithium aluminum hydride and 15 ml of tetrahydrofuran, giving the title compound as a colorless powder.

Workup

  1. customThe reaction described in Preparation 15

Sources & evidence

ORD record
ord-60dfb5e1124d4f56aaa8108b9e1e8285
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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