Triethylamine → HCID 15053582, compound

HRID 2107298Notes

Reaction equation

HRID 2107298 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[S:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=2)[CH2:4][CH2:3]1.C(N(CC)CC)C>CS(C)=O>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8]2[S:9][CH:10]=[C:11]([CH:13]=[O:14])[N:12]=2)[CH2:6][CH2:7]1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 15053564HCID 15053564, compound

Product 1

HCID 15053582HCID 15053582, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The reaction described in Preparation 44 was repeated, but using 2.4 g of 2-(4-methyl-1-piperazinyl)thiazol-4-yl-methanol, 5.4 g of sulfur trioxide pyridine complex, 3.4 g of triethylamine, and 30 ml of dimethyl sulfoxide, giving the title compound as a pale brown oil.

Workup

  1. customThe reaction described in Preparation 44

Sources & evidence

ORD record
ord-ea81416c4f0042bf9f64dc7f58dd6e6b
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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