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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107302Generated: October 29, 2026

Ethyl bromopyruvate → Ethyl 2-isopropylaminothiazole-4-carboxylate

https://huagongshe.com/reaction/2107302

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromopyruvateHCID 66144—
ReactantUrea, 1-isopropyl-2-thio-HCID 1711921—
SolventEthanolHCID 702—
ProductEthyl 2-isopropylaminothiazole-4-carboxylateHCID 15053549—

Reaction Steps

The reaction described in Preparation 42 was repeated, but using 3.7 g of isopropylthiourea, 7.4 g of ethyl bromopyruvate and 50 ml of ethanol, giving the title compound as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04933355
Source datasetuspto-grants-1990_06
ORD IDord-975a0b793e334788b6c424fd96bd50b6
Source noteuspto-grants-1990_06