Triethylamine → HCID 15053584, compound

HRID 2107303Notes

Reaction equation

HRID 2107303 reaction equation
[CH:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([CH2:10][OH:11])[N:9]=1)([CH3:3])[CH3:2].C(N(CC)CC)C>CS(C)=O>[CH:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([CH:10]=[O:11])[N:9]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 15053566HCID 15053566, compound

Product 1

HCID 15053584HCID 15053584, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The reaction described in Preparation 44 was repeated, but using 4.4 q of 2-isopropylaminothiazol-4-ylmethanol, 12.2 g of pyridine sulfur trioxide complex, 7.7 g of triethylamine and 60 ml of dimethyl sulfoxide, giving the title compound as a pale brown oil.

Workup

  1. customThe reaction described in Preparation 44

Sources & evidence

ORD record
ord-3e52fb908eda443b80e92abf9544ae89
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…