HCID 15053551, compound → HCID 15053568, compound

HRID 2107308Notes

Reaction equation

HRID 2107308 reaction equation
[CH:1]1([NH:4][C:5]2[S:6][CH:7]=[C:8]([C:10](OCC)=[O:11])[N:9]=2)[CH2:3][CH2:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH:1]1([NH:4][C:5]2[S:6][CH:7]=[C:8]([CH2:10][OH:11])[N:9]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 15053551HCID 15053551, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 15053568HCID 15053568, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction described in Preparation 15 was repeated, but using 1.2 g of ethyl 2-cyclopropylaminothiazole- 4-carboxylate, 0.2 g of lithium aluminum hydride and 20 ml of tetrahydrofuran, giving the title compound as a pale yellow oil.

Workup

  1. customThe reaction described in Preparation 15

Sources & evidence

ORD record
ord-9470319c0f5540d4a668cc0466c2fb77
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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