Triethylamine → HCID 15053586, compound

HRID 2107309Notes

Reaction equation

HRID 2107309 reaction equation
[CH:1]1([NH:4][C:5]2[S:6][CH:7]=[C:8]([CH2:10][OH:11])[N:9]=2)[CH2:3][CH2:2]1.C(N(CC)CC)C>CS(C)=O>[CH:1]1([NH:4][C:5]2[S:6][CH:7]=[C:8]([CH:10]=[O:11])[N:9]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 15053568HCID 15053568, compound

Product 1

HCID 15053586HCID 15053586, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

The reaction described in Preparation 44 was repeated, but using 1.1 g of 2-cyclopropylaminothiazol-4-ylmethanol, 3.1 g of sulfur trioxide pyridine complex, 2 g of triethylamine and 15 ml of dimethyl sulfoxide, giving the title compound as pale yellow prisms.

Workup

  1. customThe reaction described in Preparation 44

Sources & evidence

ORD record
ord-5ce569e8ef154289b24363cd759991b0
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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