Trifluoroacetic acid → HCID 178472284, compound

HRID 2107346Notes

Reaction equation

HRID 2107346 reaction equation
[PH2:1](=[O:3])[OH:2].[CH2:4]([O:6][CH:7](OCC)[O:8][CH2:9][CH3:10])[CH3:5].F[C:15](F)(F)[C:16](O)=O>>[CH2:4]([O:6][CH:7]([PH:1](=[O:2])[O:3][CH2:15][CH3:16])[O:8][CH2:9][CH3:10])[CH3:5]

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 31214Ethyl orthoformateHCID 4124402Phosphinic Acid

Product 1

HCID 178472284HCID 178472284, compoundYield 62.9%

Procedure

Using the procedure described in Example 1b, 3.3 parts of commercially available 50% aqueous phosphinic acid solution are reacted with 22.25 parts of triethylorthoformate in the presence of 0.57 parts of trifluoroacetic acid. Work up and purification by the procedures described in Example 1b gives 3.1 parts (62.9%) of ethyl diethoxymethylphosphinate of 94.7% purity.

Workup

  1. custompurification by the procedures

Sources & evidence

ORD record
ord-80aa20030b2e4b60b9aa4618f7011e23
Source dataset
uspto-grants-1990_06
Patent number
US04933478

Reaction notes

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