Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 14405368 | HCID 14405368 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 14405369 | HCID 14405369 | 80% |
Reaction Steps
55 g of 4-difluoromethoxybenzhydrol are dissolved in 440 ml of chloroform, the mixture is cooled to 0° C. and 17.5 ml of thionyl chloride in 220 ml of chloroform are added. The mixture is allowed to stand for 24 hours at room temperature and excess thionyl chloride and chloroform are removed by distillation. 47 g (80%) of 4-difluoromethoxybenzhydryl chloride are obtained as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04935414 |
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| Source dataset | uspto-grants-1990_06 |
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| ORD ID | ord-bfd17e8cadbc470a9b6c70c76719e03d |
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| Source note | uspto-grants-1990_06 |
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