2-(Dimethylamino)ethanol → HCID 13608927, compound

HRID 2107540Notes

Reaction equation

HRID 2107540 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][OH:6])[CH3:3].[C:7]([N:12]=[C:13]=[O:14])(=[O:11])[C:8]([CH3:10])=[CH2:9]>C(Cl)(Cl)Cl.ClCCCl>[C:7]([NH:12][C:13](=[O:14])[O:6][CH2:5][CH2:4][N:2]([CH3:3])[CH3:1])(=[O:11])[C:8]([CH3:10])=[CH2:9]

Participants

5

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 10942374Methacryloyl isocyanate

Product 1

HCID 13608927HCID 13608927, compoundYield 99.9%

Reagents, catalysts & solvents 2

HCID 111,2-DichloroethaneSolvent2×HCID 6212ChloroformSolvent2×

Procedure

Dimethylaminoethanol (0.89 g; 10 mmol) was dissolved in dry chloroform (20 ml) under ice-cooling, and a solution of methacryloyl isocyanate (1.11 g; 10 mmol) in 1,2-dichloroethane (5 ml) was dropwise added thereto under nitrogen stream. After completion of the addition, chloroform and 1,2-dichloroethane were evaporated under reduced pressure to give dimethylaminoethyl N-methacryloylcarbamate (2.00 g), which was recrystallized from a mixture of benzene and hexane to give colorless needle-like crystals. M.P., 71°-73° C.

Workup

  1. temperaturecooling
  2. customwere evaporated under reduced pressure

Sources & evidence

ORD record
ord-26d8c6dd725641b6914a2294e835b69a
Source dataset
uspto-grants-1990_06
Patent number
US04935413

Reaction notes

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