HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-tert-Butylphenyl)piperazine → N-(4-Tert-butylcyclohexyl)-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-tert-Butylphenyl)piperazine | HCID 781722 | — |
| Catalyst | Ruthenium dioxide | HCID 82848 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | N-(4-Tert-butylcyclohexyl)-piperazine | HCID 14553997 | — |
Reaction Steps
90 g (0.41 mole) of N-(4-tert-butylphenyl)-piperazine in 1.6 l of dioxane are hydrogenated over 5 g of ruthenium(IV) oxide at 130° C. and under 150 bar for 74 hours. Working up in the usual manner gives a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04935426 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-61024e96bc7a4bee913b9825fccb67c9 |
| Source note | uspto-grants-1990_06 |