HCID 15117875, compound → HCID 15117876, compound

HRID 2107748Notes

Reaction equation

HRID 2107748 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH2:18][C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:17])[CH3:16])=[CH:11][C:10]=1[O:23][CH2:24][C:25]1([CH3:32])[CH2:29][CH2:28][CH:27]([CH2:30][OH:31])[O:26]1)C1C=CC=CC=1>[Pd].C(O)C>[OH:31][CH2:30][CH:27]1[O:26][C:25]([CH2:24][O:23][C:10]2[CH:11]=[C:12]([C:15]([CH2:18][C:19]([CH3:22])([CH3:21])[CH3:20])([CH3:16])[CH3:17])[CH:13]=[CH:14][C:9]=2[OH:8])([CH3:32])[CH2:29][CH2:28]1

Participants

4

Reactant 1

HCID 15117875HCID 15117875, compound

Product 1

HCID 15117876HCID 15117876, compoundYield 116%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 4 g (9.1 mmole) of 1-benzyloxy-2-(5-hydroxymethyl-2-methyl-2-tetrahydrofuranylmethoxy)-4-t-octylbenzene, 1 g of 10% palladium-on-carbon and 75 ml of ethanol was shaken under an atmosphere of hydrogen at ca. 4 kg/cm2 for 3 hours. The resulting mixture was filtered, and the filtrate was evaporated in vacuo to give 3.7 g of the title compound as an oil.

Workup

  1. filtrationThe resulting mixture was filtered
  2. customthe filtrate was evaporated in vacuo

Sources & evidence

ORD record
ord-63ff32eefa76456cbeacdbd9398ba988
Source dataset
uspto-grants-1990_06
Patent number
US04935442

Reaction notes

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