Sodium Hydroxide → HCID 23673134, compound

HRID 2107910Notes

Reaction equation

HRID 2107910 reaction equation
[OH-].[Na+:2].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:11]([CH3:23])[C:12]([CH2:20][CH2:21][CH3:22])=[C:13]([C:17](=[O:19])[CH:18]=2)[C:14]([OH:16])=[O:15])=[CH:6][CH:5]=1>CO>[Cl:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[N:11]([CH3:23])[C:12]([CH2:20][CH2:21][CH3:22])=[C:13]([C:17](=[O:19])[CH:18]=2)[C:14]([O-:16])=[O:15])=[CH:8][CH:9]=1.[Na+:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14075347HCID 14075347, compound

Product 1

HCID 23673134HCID 23673134, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.42 g (0.0052 mol) of 50% aqueous sodium hydroxide is added to a suspension of 1.6 g (0.0052 mol) 6-(4-chlorophenyl)-1-methyl-2-n-propyl-4-oxonicotinic acid in 25 ml of methanol. The solution formed is allowed to stand at room temperature for 1 hr. and is concentrated in vacuo. The concentrate is dried to afford 1.5 g (88% yield) of product.

Workup

  1. customThe solution formed
  2. concentrationand is concentrated in vacuo
  3. customThe concentrate is dried

Sources & evidence

ORD record
ord-ea9e5882477940f3928c4fcb6dfe63ee
Source dataset
uspto-grants-1990_06
Patent number
US04936904

Reaction notes

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