2,5-Dichloropyridine → HCID 23045000, compound

HRID 2107948Notes

Reaction equation

HRID 2107948 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[CH2:9][CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)=[CH:4][CH:3]=1.[Cl:25][C:26]1[CH:31]=[CH:30][C:29]([Cl:32])=[CH:28][N:27]=1>C1(C)C=CC=CC=1>[ClH:25].[ClH:25].[F:24][C:21]1[CH:20]=[CH:19][C:18]([CH:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[CH2:9][CH2:10][CH2:11][N:12]2[CH2:13][CH2:14][N:15]([C:26]3[CH:31]=[CH:30][C:29]([Cl:32])=[CH:28][N:27]=3)[CH2:16][CH2:17]2)=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 276852,5-DichloropyridineHCID 797291-(4,4-Bis(4-fluorophenyl)butyl)piperazine

Product 1

HCID 23045000HCID 23045000, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

19.8 g (0.06 mole) of 1-[4,4-bis(p-fluorophenyl)butyl]-piperazine and 2.96 g (0.02 mole) of 2,5-dichloropyridine were heated together with 2 ml of toluene at 130° C. (temperature of oil bath) for 20 h.

Sources & evidence

ORD record
ord-527650e0dea040baaca100bd8b6b8ef4
Source dataset
uspto-grants-1990_06
Patent number
US04937245

Reaction notes

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