2-(2-Hydroxyethyl)pyridine → HCID 23045065, compound

HRID 2108025Notes

Reaction equation

HRID 2108025 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][OH:9].[Br:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]Br>>[Br:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][O:9][CH2:8][CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1

Participants

3

Reactant 2

HCID 76752-(2-Hydroxyethyl)pyridineHCID 81001,5-Dibromopentane

Product 1

HCID 23045065HCID 23045065, compound

Procedure

From 2-pyridineethanol (5.0 g) and 1,5-dibromopentane (16.6 ml), with a reaction time of 4 h. FCC eluting with hexane-diethyl ether (1:0→1:1) gave the title compound as a colourless oil (6.15 g), t.l.c. (ether-hexane 1:1) Rf 0.19.

Workup

  1. customwith a reaction time of 4 h
  2. washFCC eluting with hexane-diethyl ether (1:0→1:1)

Sources & evidence

ORD record
ord-1419ca70c8ed4e73b79da6473ad6466e
Source dataset
uspto-grants-1990_06
Patent number
US04937251

Reaction notes

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