HCID 70361905, compound → HCID 23045076, compound

HRID 2108030Notes

Reaction equation

HRID 2108030 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\[C:13]1[C:18]([O:19]CC2C=CC=CC=2)=[CH:17][CH:16]=[CH:15][N:14]=1>C(O)C.[Pd]=O>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]1[C:18]([OH:19])=[CH:17][CH:16]=[CH:15][N:14]=1

Participants

4

Reactant 1

HCID 70361905HCID 70361905, compound

Product 1

HCID 23045076HCID 23045076, compoundYield 99.7%

Reagents, catalysts & solvents 2

HCID 5083724Palladium monoxideCatalystHCID 702EthanolSolvent

Procedure

(Z)-2-[4-[(6-Bromohexyl)oxy]-1-butenyl]-3-(phenylmethoxy)pyridine (1.5 g) was hydrogenated over pre-reduced 10% palladium oxide on carbon (50% aqueous paste, 300 mg) in ethanol (15 ml). The catalyst was removed by filtration through hyflo and the solvent was evaporated to give the title compound as a yellow oil (1.18 g).

Workup

  1. customThe catalyst was removed by filtration through hyflo
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-111056d87a1740b4b9fe03eafc592bb3
Source dataset
uspto-grants-1990_06
Patent number
US04937251

Reaction notes

Loading…