HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 23045568, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 2-[(2-Methylpropoxy)methyl]oxirane | HCID 98155 | — |
| Reactant | 1-(2-Methylpropoxy)-3-(pyrrolidin-1-yl)propan-2-ol | HCID 6452140 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23045568 | HCID 23045568 | — |
Reaction Steps
20 g. 1-(2-Methylpropoxy)-2,3-epoxypropane are dissolved in 40 ml. ethanol and the solution is warmed to 55° C. Subsequently, in the course of an hour and while stirring, there is added dropwise a solution of 13 g. pyrrolidine in 25 ml. ethanol. The temperature should thereby not increase above 70° C. After completion of the addition, stirring is continued for 1 hour at 70° C., the reaction mixture is then evaporated and the residue is distilled in a vacuum. There are obtained 35 g. 3-(2-methylpropoxy)-1-pyrrolidinopropan-2-ol; b.p. 134° C./14 mm.Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937337 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-fbbd07111a674f5b8bec9d2be9883c85 |
| Source note | uspto-grants-1990_06 |