Sodium Hydroxide → HCID 178461614, compound

Participants

Reaction Steps

To a solution of disodium (1S,2S)-2-hydroxy-1-methanesulphonyloxypropyl phosphonate (2.78 g) in water (10 ml) an aqueous solution 1N of sodium hydroxide (10 ml, 10 mmol) was added at 15° C. The reaction mixture was kept at 15° C. for 2 hours. Evaporation of the solvent affords disodium (1R,2S)-1,2-epoxypropyl phosphonate.

Provenance & Evidence