HCID 86744054, compound → HCID 22365187, compound

HRID 2108279Notes

Reaction equation

HRID 2108279 reaction equation
[C:1]([S:9][CH:10]([CH:16]([CH2:24][CH:25]([CH3:27])[CH3:26])[C:17]([O:19]C(C)(C)C)=[O:18])[CH2:11][C:12]([NH:14][CH3:15])=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>FC(F)(F)C(O)=O>[C:1]([S:9][CH:10]([CH:16]([CH2:24][CH:25]([CH3:27])[CH3:26])[C:17]([OH:19])=[O:18])[CH2:11][C:12]([NH:14][CH3:15])=[O:13])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 86744054HCID 86744054, compound

Product 1

HCID 22365187HCID 22365187, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

2-(1-Benzoylmercapto-2-[methylaminocarbonyl]ethyl)-4-methylpentanoic acid, tert-butyl ester (D11; 0.5 g) was treated with trifluoroacetic acid (10 ml) at 0° C. for 2h and evaporated to dryness in vacuo to give 2-(1-benzoylmercapto-2-[methylaminocarbonyl]ethyl)4-methylpentanoic acid.

Workup

  1. customevaporated to dryness in vacuo

Sources & evidence

ORD record
ord-4a8ff73d1f2b4aaf8f025e84145e36e5
Source dataset
uspto-grants-1990_06
Patent number
US04937243

Reaction notes

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