HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-amino-5-methyl-1H-pyrazole-4-carbonitrile → HCID 67213296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-amino-5-methyl-1H-pyrazole-4-carbonitrile | HCID 227460 | — |
| Reactant | 1-(4-Chlorophenyl)-4,4,4-trifluorobutane-1,3-dione | HCID 2773832 | — |
| Product | HCID 67213296 | HCID 67213296 | 66% |
Reaction Steps
Reaction of 1-(4-chloro-phenyl)-4,4,4-trifluoro-butane-1,3-dione (251 mg, 1.0 mol), prepared from commercially available 4-chloro-acetophenone according to general procedure A, and commercially available 3-amino-4-cyano-5-methyl-pyrazole (122 mg, 1.0 mmol) according to general procedure B yielded the title compound as a yellow solid (222 mg, 66%). MS (ISP) 337.1 [(M+H)+]; mp 238° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514443B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-0d97937c7a9c491f818830f2d263d9c3 |
| Source note | uspto-grants-2009_04 |