Dichloromethane → 4-Methanesulfonyloxy-2-methoxymethyl-pyrrolidine-1-carboxylic Acid T-butyl Ester

HRID 210849Notes

Reaction equation

HRID 210849 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][O:15][CH3:16])[CH2:10][CH:11]([OH:13])[CH2:12]1.[CH3:17][S:18]([Cl:19])(=[O:20])=[O:21].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cl:29][CH2:30][Cl:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][O:15][CH3:16])[CH2:10][CH:11]([O:13][S:18]([CH3:17])(=[O:20])=[O:21])[CH2:12]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 19900165Tert-butyl 4-hydroxy-2-(methoxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 199002664-Methanesulfonyloxy-2-methoxymethyl-pyrrolidine-1-carboxylic Acid T-butyl Ester

Sources & evidence

ORD record
ord-42b557af30104e568ef55f23ff737a96
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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