Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | HCID 57633187 | HCID 57633187 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57633160 | HCID 57633160 | — |
Reaction Steps
The crude 2-[3-(3-chloro-propane-1-sulfonylamino)-phenyl]-N-[4-(1H-pyrrolo [2,3-b]pyridin-3-yl)-thiazol-2-yl]-acetamide was treated with neat piperidine and heated to 100° C. overnight. The reaction mixture was diluted with DMF and purified by preparative HPLC to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07514448B2 |
|---|
| Source dataset | uspto-grants-2009_04 |
|---|
| ORD ID | ord-919ec5783eda4c0fa9a9b33034708f5c |
|---|
| Source note | uspto-grants-2009_04 |
|---|
