Hydrochloric Acid → 25442-63-1

HRID 2109023Notes

Reaction equation

HRID 2109023 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:14][CH2:15][N:16]([CH2:19][CH3:20])[CH2:17][CH3:18])(=[O:13])=[O:12])=[CH:7][CH:6]=1)(=O)C.Cl>C(O)C>[CH2:19]([N:16]([CH2:17][CH3:18])[CH2:15][CH2:14][S:11]([C:8]1[CH:7]=[CH:6][C:5]([NH2:4])=[CH:10][CH:9]=1)(=[O:13])=[O:12])[CH3:20]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69065330HCID 69065330, compound

Product 1

HCID 41421425442-63-1

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

9.85 g of N-acetyl-4-(2-diethylamino-ethyl-sulphonyl)-aniline (educt XVII) are dissolved in 25 ml of ethanol and 100 ml of 3N hydrochloric acid are added. The mixture is stirred for 1 hour at reflux temperature. After cooling it is neutralised, extracted three times with methylene chloride, dried over magnesium sulphate and finally the solvent is eliminated.

Workup

  1. temperatureat reflux temperature
  2. temperatureAfter cooling it
  3. extractionextracted three times with methylene chloride
  4. dry with materialdried over magnesium sulphate

Sources & evidence

ORD record
ord-f9ce0c221a7944b390771b1a679bba56
Source dataset
uspto-grants-2009_04
Patent number
US07514468B2

Reaction notes

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