Isopropanol → HCID 11372072, compound

HRID 2109080Notes

Reaction equation

HRID 2109080 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][C:15]([F:18])([F:17])[F:16])[CH2:10][C:11]([OH:13])=[O:12])=[CH:5][C:4]=1[C:19]([F:22])([F:21])[F:20])#[N:2].[CH:23](O)([CH3:25])[CH3:24]>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][C:15]([F:16])([F:17])[F:18])[CH2:10][C:11]([O:13][CH:23]([CH3:25])[CH3:24])=[O:12])=[CH:5][C:4]=1[C:19]([F:21])([F:20])[F:22])#[N:2]

Participants

3

Reactant 2

HCID 3776IsopropanolHCID 57633731N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine

Product 1

HCID 11372072HCID 11372072, compound

Procedure

Synthesized according to example 3 N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine and isopropanol: 1H NMR (300 MHz, CD3OD) δ 7.81-7.73 (m, 1H), 7.17-7.09 (m, 2H), 5.04 (sept, J=6.3 Hz, 1H), 4.38 (s, 2H, overlapped with 4.35), 4.35 (q, J=9.0 Hz, overlapped with 4.38, 2H), 1.23 (d, J=6.1 Hz, 6H).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-8c3e12ca01a54561a39129bb1add8388
Source dataset
uspto-grants-2009_04
Patent number
US07514470B2

Reaction notes

Loading…