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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109236Generated: October 26, 2026

4,5-Dihydro-2-thiazolamine → 2,3-Dihydro-imidazo[2,1-b]thiazole-5-carbaldehyde

https://huagongshe.com/reaction/2109236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,5-Dihydro-2-thiazolamineHCID 15689—
Reactant3-cyclopropyl-2-methyl-3H-imidazole-4-carbaldehydeHCID 21097307—
Reactant2-Bromo-3-isopropoxy-propenalHCID 53416634—
Product2,3-Dihydro-imidazo[2,1-b]thiazole-5-carbaldehydeHCID 21097254—

Reaction Steps

2,3-Dihydro-imidazo[2,1-b]thiazole-5-carbaldehyde was prepared from 4,5-dihydro-thiazol-2-ylamine and and 2-bromo-3-isopropoxy-propenal in the same manner as cyclopropyl-2-methyl-3H-imidazole-4-carbaldehyde (Example 45).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-1e6ee11fa4034a43a85dafb002eb883f
Source noteuspto-grants-2009_04