Tert-Butylamine → HCID 21097313, compound

HRID 2109252Notes

Reaction equation

C1(C(N)=O)CC1.[C:7]([NH2:11])([CH3:10])([CH3:9])[CH3:8].[CH:12]1([C:15]2N(C)[C:18]([CH:21]=[O:22])=[CH:17][N:16]=2)[CH2:14][CH2:13]1>>[C:7]([N:11]1[C:18]([CH:21]=[O:22])=[CH:17][N:16]=[C:15]1[CH:12]1[CH2:14][CH2:13]1)([CH3:10])([CH3:9])[CH3:8]

Participants

Reactant 3

HCID 6385Tert-Butylamine

HCID 80376Cyclopropanecarboxamide

HCID 210972742-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde

Product 1

HCID 21097313HCID 21097313, compound

Procedure

3-tert-Butyl-2-cyclopropyl-3H-imidazole-4-carbaldehyde was prepared from cyclopropyl carboxamide and tert-butylamine in the same manner as 2-cyclopropyl-3-methyl-3H-imidazole-4-carbaldehyde (Example 46).

Sources & evidence

ORD record: ord-e65b76eaa2fd45d38650d1db6845c208
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07514458B2

Reaction notes

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