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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109306Generated: October 30, 2026

2-Methoxy-5-(trifluoromethyl)aniline → 3-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamide

https://huagongshe.com/reaction/2109306

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxy-5-(trifluoromethyl)anilineHCID 600637—
Reactant3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl esterHCID 58861445—
Product3-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamideHCID 21097092—

Reaction Steps

Example 154 was prepared from 2-methoxy-5-trifluoromethyl-phenylamine and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 546 [C30H26F3N5O2+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-63178c02de024c15946453da0a69554c
Source noteuspto-grants-2009_04