HRID2109307

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21097297

未命名化合物

结构：CCc1c(-c2cn(-c3cc(C(=O)OC)ccc3C)cn2)cnn1-c1ccccc1

HCID58861445

未命名化合物

PRODUCTS

生成物

结构：CCc1c(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)cc(C#N)c4OC)ccc3C)cn2)cnn1-c1ccccc1

HCID21097111

未命名化合物

PROCEDURE

实验过程

Example 155 was prepared from 3-amino-5-tert-butyl-2-methoxy-benzonitrile and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 559 [C34H34N6O2+H]+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-84ec8aa15a704cbf83ab06c4f80f75ba
来源数据集: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07514458B2
来源说明: uspto-grants-2009_04

反应 SMILES

[NH2:1][C:2]1[C:3]([O:14][CH3:15])=[C:4]([CH:7]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:9]=1)[C:5]#[N:6].C[O:17][C:18](=O)[C:19]1[CH:24]=[CH:23][C:22]([CH3:25])=[C:21]([N:26]2[CH:30]=[C:29]([C:31]3[CH:32]=[N:33][N:34]([C:38]4[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=4)[C:35]=3[CH2:36][CH3:37])[N:28]=[CH:27]2)[CH:20]=1>>[C:10]([C:8]1[CH:7]=[C:4]([C:5]#[N:6])[C:3]([O:14][CH3:15])=[C:2]([NH:1][C:18](=[O:17])[C:19]2[CH:24]=[CH:23][C:22]([CH3:25])=[C:21]([N:26]3[CH:30]=[C:29]([C:31]4[CH:32]=[N:33][N:34]([C:38]5[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=5)[C:35]=4[CH2:36][CH3:37])[N:28]=[CH:27]3)[CH:20]=2)[CH:9]=1)([CH3:12])([CH3:11])[CH3:13]