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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109307Generated: October 25, 2026

3-Amino-5-(tert-butyl)-2-methoxybenzonitrile → N-(5-tert-Butyl-3-cyano-2-methoxy-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamide

https://huagongshe.com/reaction/2109307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-5-(tert-butyl)-2-methoxybenzonitrileHCID 21097297—
Reactant3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl esterHCID 58861445—
ProductN-(5-tert-Butyl-3-cyano-2-methoxy-phenyl)-3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzamideHCID 21097111—

Reaction Steps

Example 155 was prepared from 3-amino-5-tert-butyl-2-methoxy-benzonitrile and 3-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester (Example 151) in the same manner as Example 151. ESI MS m/z 559 [C34H34N6O2+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514458B2
Source datasetuspto-grants-2009_04
ORD IDord-84ec8aa15a704cbf83ab06c4f80f75ba
Source noteuspto-grants-2009_04