Methylamine → HCID 21097210, compound

HRID 2109316Notes

Reaction equation

[C:1]([C:5]1[CH:6]=[C:7]([NH:36][S:37]([CH3:40])(=[O:39])=[O:38])[C:8]([O:34][CH3:35])=[C:9]([NH:11][C:12](=[O:33])[C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[C:15]([N:20]3[CH:24]=[C:23]([C:25]4[CH:26]=[N:27][C:28]([CH:31]=[CH2:32])=[CH:29][CH:30]=4)[N:22]=[N:21]3)[CH:14]=2)[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:41][NH2:42]>>[C:1]([C:5]1[CH:6]=[C:7]([NH:36][S:37]([CH3:40])(=[O:38])=[O:39])[C:8]([O:34][CH3:35])=[C:9]([NH:11][C:12](=[O:33])[C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[C:15]([N:20]3[CH:24]=[C:23]([C:25]4[CH:26]=[N:27][C:28]([CH2:31][CH2:32][NH:42][CH3:41])=[CH:29][CH:30]=4)[N:22]=[N:21]3)[CH:14]=2)[CH:10]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

Reactant 2

HCID 6329Methylamine

HCID 21097370HCID 21097370, compound

Product 1

HCID 21097210HCID 21097210, compound

Procedure

Example 162 was prepared from N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-3-[4-(6-vinyl-pyridin-3-yl)-1,2,3-triazol-1-yl]-benzamide (Example 151) and methylamine in the same manner as Example 151. ESI MS m/z 592 [C30H37N7O4S+H]+.

Sources & evidence

ORD record: ord-c18b306d7f244644917561d68bcaedcb
Source dataset: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07514458B2

Reaction notes

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