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AR-R-17779 → (R)-3'-[2-(3-Pyridyl)thiophen-4-yl]spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | AR-R-17779 | HCID 5310971 | — |
| 反応物 | 3-(4-bromo-2-thienyl)Pyridine | HCID 22180781 | — |
| 生成物 | (R)-3'-[2-(3-Pyridyl)thiophen-4-yl]spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one | HCID 11325305 | — |
反応手順
The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 4-bromo-2-(3-pyridyl)thiophene. The title compound (800 mg) was obtained as a pale-yellow solid, m/z 342 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07514567B2 |
| 出典データセット | uspto-grants-2009_04 |
| ORD ID | ord-062cd926fe83459880549e568219071a |
| 出典メモ | uspto-grants-2009_04 |